Karyn Lyons was born in New Haven, Connecticut, in 1981. She received a BA from American University in Washington, D.C., and pursued postgraduate studies at The School of the Museum of Fine Arts in Boston, Massachussetts. 

Lyons' recent solo and group exhibitions include "Landline" at TURN Gallery in New York, New York (2025); "The End of the Night" at Anat Ebgi in Los Angeles, California (2024); "The Secret History" at Gladstone Gallery in New York, New York (2024); "Dreaming of Eden" at Timothy Taylor in New York, New York (2023); "The Trespasser And Other Tales" at TURN Gallery in New York, New York (2023); "As Tears Go By" at Stems in Paris, France (2023); Tennis Elbow at The Journal Gallery in New York, New York (2022); "The Power to Dream" at Galerie Hussenot in Paris, France (2022); "Ojos De Perro Azul" at Marinaro in New York, New York (2022); "Through a glass, darkly" at Carl Kostyál in Milan, Italy (2022); "Among Flowers" at TURN Gallery in New York, New York (2022); "SUPERPOWER" at Sim Smith in London, United Kingdom (2022); "Figuration Now!" at Stems Gallery in Brussels, Belgium (2022); "I Do My Own Stunts" at Spazio Amanita in Los Angeles, California (2022); "Under the Spell" at TURN Gallery in New York, New York (2021); "Mother and Child" at Friends Indeed Gallery in San Francisco, California (2021); "Sweet Jane in Fields of Daisies" at Philips in Hong Kong, China (2021); "Summer Sun" at The Journal Gallery in East Hampton, New York (2021); "Towards a More Beautiful Oblivion" at Fredericks & Freiser in New York, New York (2021); "Frozen Time" at Galleria Annarumma in Naples, Italy (2021); and "Nostalgia" at TURN Gallery in New York, New York (2021). 

Karyn Lyons lives and works in New York, New York.